If you can get away with applications being in sub folders, that's great. I use list view almost exclusively, unless I need previews. Once you open a new window you have to start all over again! GRRR! Then of course you can't sort the column by date modified, etc. I dislike the column view as it's implemented in OS X (Greg's Browser was better) and I REALLY dislike the column view in file dialog boxes, since there's too many columns, you have to resize them to see long names (without hovering over each file), and it takes you too far back in the file path. I think the OS X Finder is poorly designed in general. I use Fruitmenu, and many of my often, and not so often used apps are lunched from there. I do use the keyboard shortcuts, but the rest of the Go menu is somewhat redundant, as you have these folders in your sidebar. The Go menu is a lame excuse for the fact that Apple decided that the Apple menu was out dated. I don't even open my hard drive very often. I rarely open the Applications folder, being that it is such a mess, if I don't have to.
That's fine, but you still have to dig through folders.